SMARCD1 and atherosclerosis: Macrophages are often important drivers of atherosclerosis due to their role in inflammation, which is thought to contribute to the onset of the disorder [65,66] It was found that in a mouse model, BAF60a was down-regulated in plaque macrophages in advanced atherosclerosis, and generation of BAF60a-deficient macrophages resulted in mitochondrial dysfunction, which is associated with inflammation [67].