GPT and Thrombocytopenia: In 1989, Swanepoel et al. (36) proposed a model that predicted a >90% fatal outcome if patients had any of the following: leukocytosis (leukocytes >10,000/mm3), thrombocytopenia (platelets <20,000/mm3), AST >200 U/L or ALT >150 U/L, aPTT >60 seconds, or fibrinogen <110 mg/dL.