KIF11 and lymphedema: Moreover, KIF11 gene mutations have been identified in patients with various retinal diseases including MLCRD (microcephaly, lymphedema, and chorioretinal dysplasia), CDMMR (chorioretinal dysplasia, microcephaly, and mental retardation), and FEVR (familial exudative vitreoretinopathy).[35, 36] These accumulating results, together with our finding that the KIF11 is required for the maintenance of photoreceptor cilium integrity and retinal homeostasis (Figure 7), indicate that this kinesin might serve as a marker for the diagnosis of retinal diseases.