The low overall detection sensitivity of the α‐syn SAA for LBP in this ADAD cohort is in line with the previously reported reduced sensitivity of these assays for the Amg‐LBP variants and other conditions in which the LBP is only focally present (e.g., limited to the lower brainstem or the olfactory areas) compared to the virtually full sensitivity in cases with a neocortical or limbic stage of LB disease pathology.26, 27, 28. Here, AMELX is linked to Low back pain.