Despite the markedly smaller sample size for analysis of the MRI data (approximately 8% of participants with exome data), nominal associations (PCauchy < 0.05) with LV traits were also detected for ALPK3: LV end diastolic and systolic volumes and measures of hypertrophy (maximum left ventricular mass (LVMmax) and maximum free wall mass (FWmax)). This evidence concerns the gene ALPK3 and hypertrophy.