The infusion of this peptide prevented septic shock in different animal models, limiting the amount of IL-6 cytokine, nitric oxide (NO) production and decreasing renal, lung and liver damage, along with IκB kinase pathway inhibition, suggesting that Ang-(1–7) ameliorate sepsis-induced organ injury likely through the inhibition of an inflammatory response (Tsai et al., 2021; Garcia et al., 2023). This evidence concerns the gene ANG and Sepsis.