Similarly, Myla and HH cell lines reflect advanced MF, while Mac2A and PB2B are indicative of CD30+ LPDs, and MJ and Hut102 lines are associated with Adult T-cell Leukemia/Lymphoma (ATLL), demonstrating the broad spectrum of CTCL manifestations (Gill et al., 2022). This evidence concerns the gene TNFRSF8 and primary cutaneous T-cell non-Hodgkin lymphoma.