The Mannose-Binding Lectin 2 (MBL2) mouse model, utilizing C57BL/6 mice as a syngeneic platform, creates an auto transplantation model for CTCL by injecting MBL2 lymphoma cells and inducing inflammation with dinitrofluorobenzene (DNFB). The gene discussed is MBL2; the disease is primary cutaneous T-cell non-Hodgkin lymphoma.