A nested case-control analysis within a prospective study of 3,842 Swiss adults without baseline diabetes followed for 5.5 years on average showed that diabetes risk increased with highest vs. lowest quartile of baseline IL-6 (OR 1.58 [1.02 – 2.45]) and CRP (OR 4.63 [2.85 – 7.53]) (130). The gene discussed is CRP; the disease is diabetes mellitus.