However, in the case of a 44-year-old patient with intermittent hypercalcaemia and two intron−exon splice junction mutations (IVS5 + 1G>A and IVS6–2A>G) of CYP24A1, an analysis of family members suggested autosomal dominant inheritance with partial penetrance (25). Here, CYP24A1 is linked to Hypercalcemia.