HLA-C and neoplasm: Regarding the potential function of epigenetic regulators in many aspects of the tumor microenvironment and immune cycle, epigenetic drugs such as 5-AzaC may induce immunogenic cell death (ICD) of cancer cells, enhance the expression of various TAAs, MHC molecules, and the generation of APCs, thus enhancing the recognition of tumor target cells by immune cell activation and effector T cells.