Injection of early gestating rats with polynosinic-polycytidilic acid [Poly (I:C)] – a double-stranded RNA (dsRNA) analog that mimics viral infection – induced hypomethylation at the transcriptional repressor methyl-CpG-binding protein 2 (MeCP2) promoter in the offspring [71]. The gene discussed is MECP2; the disease is viral infectious disease.