Therefore, we suggested that the genes mentioned above, including five peak-related genes (PCK1, APOA4, APOA1, NTRK2, and KIT) and four conservative genes (PCK1, INHBE, MAMDC2, and ANXA13), are potential hub genes for the pathogenesis and treatment of FLHS (Table 3). This evidence concerns the gene MAMDC2 and Floating-Harbor syndrome.