As shown in Table 1 below, chi-square tests revealed 16 clinical factors that were statistically significant, including blood tumors, organ transplantation, immune-related diseases, respiratory failure, chronic kidney disease, hypoalbuminemia, mixed infections, immunosuppressant use, long-term steroid use, surgical history, ground-glass opacity (GGO) on chest CT, mediastinal lymph node enlargement, pleural effusion, lymphocyte reduction, elevated C-reactive protein (CRP), and positive PCR (P < 0.05). The gene discussed is CRP; the disease is Pleural effusion.