In addition, gene sets related to the response to heavy metals and metallothionein (MT) signaling (driven by MT1G, MT2A, MT1M) were more highly expressed in resilient compared to AD, while genes related the innate and adaptive immune system and TYRO protein tyrosine kinase-binding protein (TYROBP) signaling were more highly expressed in AD compared to resilience. Here, TYROBP is linked to Alzheimer disease.