Of the remaining variants (14/36 variants, 39%), 3 were enriched in the PPMI PD cohort (3/36 variants, 8%) representing 2 variants seen in multiple PEG subjects in the GALC (7 subjects) and TSC1 (5 subjects) genes, as well as the highest ranked FBXO7 variant based on the calculated disease severity x pesticide exposure score (Supplementary Table 5). The gene discussed is TSC1; the disease is Parkinson disease.