Notably, virtually all pathways associated with tumor progression, intercellular communication, and immunity, including the JAK-STAT signaling pathway, ECM-receptor interaction, Chemokine signaling pathway, and T cell receptor signaling pathway, were significantly enriched in cluster 2 (Figure 4I, p<0.05), which may account for the poorer prognosis. The gene discussed is SOAT1; the disease is neoplasm.