Like Gc deficient hosts (Fig. 1C) or WT mice gavaged with Gc-/- fecal matter (Fig. 2D-E and Supplementary Fig. 3A and B), mice fed with a VitD3 high diet did not exhibit increased tumor resistance if rendered deficient in T and B cells, cDC1 or MyD88 (Fig. 3E). This evidence concerns the gene MYD88 and neoplasm.