CAD and infection: To accomplish their infection cycle, plant (+)RNA viruses are expected to code for: (i) one or more replication proteins, including the core RNA-dependent RNA polymerase (RdRp); (ii) one or more movement proteins (MPs) to interact with PD components for cell-to-cell and/or long-distance movement; (iii) RNA silencing suppressor(s) to suppress the plant’s innate defense system against viruses; and (iv) capsid proteins (CPs) for encapsidation of the genomic (g)RNA(s) [1].