These include benign (e.g., papillary adenoma), indolent (e.g., clear cell papillary RCC), low malignant potential (e.g., eosinophilic solid and cystic RCC, mucinous tubular and spindle cell carcinoma, TCEB1-mutation RCC), malignant potential (e.g., papillary RCC, Tubulocystic RCC) and malignant and highly aggressive (e.g., collecting duct RCC, FH deficient RCC, TFE3-translocation RCC) [21]. Here, ELOC is linked to renal cell carcinoma.