We reasoned that the effect of OE would be better resolved in a cell line with lower basal expression of both proteins than MDA-MB-231 cells, and we therefore repeated the experiments in MCF10A non-cancer mammary epithelial cells, in which CD147 OE has previously been shown to lead to invasiveness and formation of filopodia-like structures (Grass et al., 2012) (Fig. S2). Here, BSG is linked to cancer.