MAPT and supranuclear palsy, progressive, 1: Given the more severe motor and oculomotor impairment seen amongst PSP-RS patients, we expected to find increased tau pathology in subcortical and brainstem regions compared with PSP-SL, as previously reported in another study.10 However, our analysis revealed similar neuronal tau burden in subcortical and brainstem regions in PSP-SL and PSP-RS, with both groups showing severe pathology.