TGM2 and cancer: TG2 was also linked to cancer cell survival, poor prognosis and chemotherapy resistance (Akimov and Belkin, 2001; Grigoriev et al., 2001; Iacobuzio-Donahue et al., 2003; Martinet et al., 2003; Mangala et al., 2007; Chen et al., 2010; Meshram et al., 2017; Lee et al., 2018; Valdivia et al., 2023).