PAK1 and breast neoplasm: PAK1 is amplified in several human cancer types, including 30-33% of breast tumor samples and cancer cell lines ((Shrestha et al., 2012), reviewed in(Eswaran, Li, Shah, & Kumar, 2012; Kumar, Gururaj, & Barnes, 2006; Molli, Li, Murray, Rayala, & Kumar, 2009)).