PRL is involved in tumor progression by increasing cell proliferation and angiogenesis, and by reducing apoptosis (reviewed in (Clevenger & Rui, 2022; Jacobson, Hugo, Borcherding, & Ben-Jonathan, 2011; Mujagic, Srabovic, & Mujagic, 2009; Schuler & O'Leary, 2022; Tworoger & Hankinson, 2006, 2008; Wagner & Rui, 2008)). Here, PRL is linked to neoplasm.