Initially, we identified 3 genes (SLC22A5, C2, and GPC2) whose expression levels in whole blood were found to be correlated with doctor-diagnosed COPD (corrected for P-value by Bonferroni, P_HEIDI≥0.01, see Supplementary Table 3 for detailed data). The gene discussed is SLC22A5; the disease is chronic obstructive pulmonary disease.