C3 and inflammatory bowel disease: In the IBD dataset, we found that the VCAM1, SERPING1, C3 and CLU genes were positively correlated with B cells naive, macrophages M0, activated dendritic cells, neutrophils and T cells follicular helper; VCAM1, SERPING1 and CLU showed negative correlation with resting dendritic cells, eosinophils, M2 macrophages, monocytes, CD4 memory resting T cells and T cells regulatory (Tregs); CD55 was positively correlated with M0 macrophages, M1 macrophages and neutrophils and negatively correlated with resting dendritic cells, eosinophils and monocytes (Figure 7G) by correlation analysis.