Researchers indicate that PAX6 rs644242 [32], ZC3H11B rs4373767 [33,34] and BICC1 rs7084402 [33,35], VIPR2 rs885863 [36] and rs6979985 [37], ZMAT4 rs7829127 [36], TNKS rs4840437 and rs6989782 [38], PDGFRA rs2114039 [39], SOX2 rs4575941 [40], FGF10 rs339501, rs2973644, and rs 79002828 [41] are associated with severe myopia (moderate and extreme myopia). This evidence concerns the gene ZMAT4 and myopia.