A myriad number of antibodies are discovered that cause myositis, they are ACA, antibodies against anti‐Ku, PM/scl, anti‐U3‐RNP (fibrillarin) antibodies, anti‐RNAP III, anti‐RuvBL1/2 (pontin, reptin), anti‐scl70, anti‐PL12, anti‐PL7, anti‐SRP.47 The gene discussed is RUVBL1; the disease is myositis disease.