In DCM rats, scutellarin enhances autophagy to upregulate the expression of Beclin-1 and LC3-II and downregulate the expression of caspase-3, caspase-12, Bax, and Cyt-C to alleviate the symptoms of DCM (Su Y. et al., 2022). The gene discussed is CASP12; the disease is familial dilated cardiomyopathy.