NR1H4 and metabolic dysfunction-associated steatohepatitis: Geniposide and chlorogenic acid, the main ingredients in Yinchenhao Decoction, also have significant effects in regulating the gut microbiota and thus affecting the FXR in order to alleviate Nonalcoholic Steatohepatitis (NASH) through the gut-liver axis (Li et al., 2023).