GPT and Decreased total leukocyte count: In addition, Grades 3–4 AEs were neutropenia (30.0%), leukopenia (25.0%), secondary hypertension (4.0%), alanine aminotransferase increase (3.0%), diarrhea (2.0%), hand‐foot syndrome (2.0%), proteinuria (2.0%), anemia (2.0%), aspartate aminotransferase increase (1.0%), and thrombocytopenia (1.0%).