In fact, Kp is currently listed amongst the most dangerous nosocomial multidrug-resistant (MDR) pathogens, grouped under the acronym ‘ESKAPE’,2 and considered a global health priority.3 In particular, a single Kp strain known as ST (Sequence Type) 258 has acquired resistance to carbapenems, last-resort antibiotics for the treatment of MDR infections, and has spread globally, becoming endemic in multiple countries.1,3–5. This evidence concerns the gene NPPA and infection.