THBS3 and lung cancer: However, decreased expression of “GPX1” (OR 2.35; 95% CI 1.63–3.39; P = 5.42 × 10−6) and “THBS3” (OR 1.50; 95% CI 1.30–1.73; P = 3.30 × 10−8) were found to be associated with the higher risk of lung cancer and gastric cancer.