NLRP3 and metabolic dysfunction-associated steatotic liver disease: Employing RT-qPCR and Western blot analysis, we observed a pivotal modulation within the liver tissues of NAFLD rats: knockdown of circSOD2 significantly elevated miR-532-3p expression, concurrently with a pronounced suppression of TXNIP and NLRP3 levels (Fig. 9A, B).