FGF1 and diabetes mellitus: It was concluded that the beneficial effects on myocardial function and structure of single i.v. injections of hUC-MSCs at earlier and later time-points following induction of DM are accompanied by preservation of the expression of the anti-fibrotic miRNA, miR-133a, prevention of the up-regulation of pro-fibrotic mRNAs and increased expression of the anti-fibrotic factor FGF-1.