Besides, genus Parasutterella was positively related with inflammatory cytokines like lipopolysaccharide and interleukin (IL)-8 but negatively with IL-10 in type 2 diabetes mellitus (T2DM) mice, while probiotic treatment maintained barrier integrity and ameliorated inflammation through decreasing enrichment of genus Parasutterella [55]. The gene discussed is IL10; the disease is type 2 diabetes mellitus.