MT-CO1 and cancer: Maintenance of more proliferation-competent precursor-like TILs upon addition of COXi was independently confirmed in seven patients with cancer by flow cytometry analysis, which demonstrated a relative increase in stem-like CD39−TCF1+ cells and a concomitant decrease in TOX+TCF1− cells in the COXi group (Fig. 5f,g and Extended Data Fig. 6k,l).