PRC1 and AL amyloidosis: Our survey of a large database of different types of solid cancer (Extended Data Fig. 9) as well as of data from several cohorts of patients with multiple myeloma (Extended Data Fig. 10) indicates that low expression levels of genes encoding canonical PRC1 subunits is associated with poor patient prognosis, consistent with a putative suppressive role for PRC1 in these tumour types.