These results align with our previous findings, where the IronQ preconditioning of MSCs exhibited its anti-inflammatory effects by inhibiting the activity of the Mincle/syk signaling pathway, suppressing inflammatory factor production in macrophages, and promoting their polarization into M2 macrophages in mouse models of intracerebral hemorrhage (ICH)24. This evidence concerns the gene CLEC4E and intracerebral hemorrhage.