In the training cohort, the univariate logistic regression analysis indicated that WBC, ALT, AST, TBIL, PT, PTA, INR, CTP scores, MELD scores, treatment modality, shock, hepatic failure, hepatic encephalopathy, ascites and postoperative rebleeding were significantly associated with 6-week mortality in active EGVB patient who underwent emergency endoscopic treatment with endotracheal intubation. The gene discussed is GPT; the disease is liver failure.