WRN and neoplasm: We identified 42 and 16 TSGs monoallelically deleted in P2 and P5, respectively, including several TSGs deleted in both tumor samples (ARHGEF10, CDKN1B, ETNK1, ETV6, LEPROTL1, NRG1, PTPN6, and WRN) and many TSGs co-deleted in the same subclone as well as across multiple subclones (Fig. 4a, Supplementary Fig. 24a, and Supplementary Data 4).