UBE2T, functioning as an E2 enzyme, has been identified as a crucial regulator of tumor advancement in various types of cancer, including gastric cancer (Yu et al. 2021), hepatocellular carcinoma (Sun et al. 2020), pancreatic cancer (Jiang et al. 2023), lung adenocarcinoma (Zhu et al. 2021), retinoblastoma (Xu et al. 2022), and glioblastoma (Huang et al. 2020). This evidence concerns the gene UBE2T and lung adenocarcinoma.