For example, TNBC exhibits stromal tumor-infiltrating lymphocytes, programmed cell-death ligand 1 (PD-L1) expression, and immunosuppressive gene activity.6-8 In the metastatic setting, the addition of pembrolizumab to chemotherapy improved progression-free survival and overall survival (OS) in patients with TNBC whose tumors expressed PD-L1 with a combined positive score of 10 or more.9,10. Here, CD274 is linked to neoplasm.