In their study among healthy adults whose parents had a history of T2DM,Jiang et al., showed adiponectin level as a strong risk marker for prediabetes andexplained this by the fact that adiponectin is evident during the transition fromnormoglycemia to prediabetes at a much earlier stage of pathogenesis, due to itswell-known association with diabetes risk17. Here, ADIPOQ is linked to prediabetes syndrome.