In continuation of our previous study that investigated alterations of global proteomes/phosphoproteomes in BAG3‐depleted U251 and U343 GBM cells, we now identified the BAG3 interactomes in both cell models to determine inasmuch the different oncogenic functions may be functionally coupled to BAG3‐dependent networks via direct target protein stabilization/degradation. Here, BAG3 is linked to glioblastoma.