Results: Acoustophoresis enabled enrichment and characterizationof phenotypic CTCs (EpCAM+, Cytokeratin+, DAPI+, CD45–/CD66b–) in allpatients with metastatic prostate cancer and detected CTC-clusterscomposed of only CTCs or heterogeneous aggregates of CTCs clusteredwith various types of white blood cells in 9 out of 12 patients. The gene discussed is PTPRC; the disease is metastatic prostate carcinoma.