The adverse events included elevated creatine kinase (35.83%), rash (9.2%), pruritus (6.4%), increased AST (6.4%), increased ALT (6.9%), leukopenia (5.8%), anemia (3.5%), stomatitis (2.3%), and diarrhea (4.6%). The gene discussed is GPT; the disease is Decreased total leukocyte count.