BCMA, CD38 and SLAMF7 represent three key antigens in the biology of MM; the first plays a key role in B cell maturation and differentiation into PCs and is upregulated in disease progression from MGUS to SMM and active MM (15); the second is uniformly expressed on PCs and is involved in modulating immune cell activation and migration (9), while the latter is involved in the development of immune system and promotes PCs proliferation and growth (13). Here, CD38 is linked to Miyoshi myopathy.