Furthermore, by Next Generation Sequencing (NGS) analyses non-synonymous point mutations of epigenetic regulators such as lysine demethylases KDM6A/UTX and KDM6B/JMJD3, histone methyltransferases MMSET and MLL and homeobox protein Hox-A9 (HOXA9) have been uncovered in MM cells (67, 68). This evidence concerns the gene HOXA9 and Miyoshi myopathy.