MAP2K7 and skin squamous cell carcinoma: The effect of the RAS/RAF/MEK/ERK signaling pathway on the pathogenesis of cSCC was evaluated and in this evaluation, researchers evaluated how defects in the protein signaling pathway led to uncontrolled growth, immense cell proliferation, evasion of apoptosis, and cancer cell survival, which are like biomarkers of cSCC (Yang and Liu, 2017[186]).