Additionally, M2 macrophage-derived exosomes carrying miR-370 alleviate asthma progression by suppressing the fibroblast growth factor-1 (FGF1) 1/MAPK/STAT1 axis in airway smooth muscle cells, resulting in the inhibition of abnormal proliferation, invasion, and the production of fibrosis-related proteins (Li et al., 2021). This evidence concerns the gene STAT1 and asthma.