In particular, SCD had lower NfL levels (14.69 ± 6.07) compared to other groups: SCD FU (17.05 ± 9.02), MCI (18.51 ± 9.80), MCI FU (17.06 ± 7.02), AD (27.61 ± 25.09) and AD FU (33.41 ± 16.88) (Figure 1B). The gene discussed is NEFL; the disease is Alzheimer disease.